Every class in the Senior School was encouraged to organise a fund-raising event during Lent and students came up with a range of innovative ideas.
They ranged from a carnival to a toast sale, a hot chocolate stall, a waffle and doughnut sale, a chocolate bunny raffle and filling a room with balloons which all contained a raffle ticket.
One of the most popular events was a Top of the Pops-style show which involved 48 students performing and backstage.
The money will be shared between six charities: When You Wish Upon A Star, a charity which specialises in making dreams come true for sick children with life-threatening illnesses; Cancer Research; British Heart Foundation; Umbrella, a Derby charity supporting disabled children, young people and their families; Epilepsy Action and YMCA Derbyshire.
Denise Gould, headteacher at Derby High School, said she was proud of all the students for their many contributions.
She said: “The students all threw themselves into organising lots of fantastic events which they thoroughly enjoyed taking part in.
“They came up with some great ideas and the Top of the Pops show was particularly popular with the whole senior school community.
“The money raised will benefit six deserving charities and we hope it will help to make real a difference to the people who benefit from them.”